English scientific name of the compound (2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl )tetrahydrofuran-2-carbonitrile
Literary name of the compound (2R,3R,4S,5R)-2-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-( hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS number 1191237-69-0
Molecular formula C12H13N5O4
Molecular weight 291.263
Exact quality 291.097
LogP -1.27552
PSA 149.92
use
GS-441524 is a small molecule with a scientific name of nucleoside triphosphate competitive inhibitor, which shows strong antiviral activity against many RNA viruses.
It can inhibit the replication of several different types of RNA viruses, such as zoonotic severe Chemicalbook acute respiratory syndrome (SARS) coronavirus, Middle East respiratory syndrome virus, Ebola virus, Lassa fever virus, Junin virus and respiratory syndrome
Cytoviruses, etc., while having low cytotoxicity in a wide range of cell lines.
Product Description
|
|
Product name |
441524 |
Molecular formula |
C12H13N5O4 |
Molecular weight |
291.26 |
Appearance |
White to off-white powder |
Purity |
≥99.00% |
Alpha-isomer |
≤0.10% |
O-Bn derivative |
≤0.30% |
N-Bn derivative |
≤0.30% |
Maximum single impurity |
≤0.30% |
Loss on drying |
≤1.0% |
Residue on ignition |
≤0.5% |